Data Exchange with CAIR2

What benefits does CAIR2 have for DX sites/ users?

  • Submissions from your EHR to CAIR2 will be smoother, and messages will be less prone to being rejected. 
  • Patient and dose information sent from your EHR will be available in near real-time (within seconds).
  • DX messages sent to CAIR2 can now decrement from CAIR2 inventory but you will need to contact the CAIR DX Staff at to get this functionality turned on for your practice.
  • Also, because the new software will be able to return HL7 ACK (indicating message status) messages to the submitter for each message received, Sites should discuss with their EHR vendors whether such messages can be received and displayed by their EHR systyems for data quality monitoring purposes.  If your Site is submitting through a Sending Facility (SF), you should also consult with your SF contact to determine whether the ACK messages returned by CAIR2 to the SF can be forwarded back to your EHR system. 
  • If ACK messages are not available in your EHR, new functionality in CAIR2 will allow 'Power' users at your Site to monitor data exchange activities.  'Power' users will be oriented to this new functionality during the required CAIR2 trainings but more extensive training and training materials on the use of this functionality are offered on the CAIR User Guides and Training Videos page .  A ‘DX Quality Assurance’ user role is also available to allow your technical and/or QA staff to monitor your Site's data exchange activity.   If your Site doesn't currently have a 'Power' user and/or would like to enroll a 'DX Quality Assurance' user, go to CAIR Account Update website to request user accounts for your staff. 

Do users need to be trained to use CAIR2? 

  • Yes.  All 'Power" and 'Regular' Users who access CAIR through the web interface will need to be trained before being given access to CAIR2. In contrast, ‘Read-Only and ‘DX QA’ users can access CAIR2 without formal training but can access the CAIR User Guides and Training Videos page for training resources.

Back to top

My site is interested in bi-directional data exchange (BiDX).  When will that be available and how should we prepare?

  • CAIR2 now allow patient information to be returned to EHR systems through a process called bi-directional data exchange (BiDX). This involves submission by the EHR to CAIR2 of a patient query message and the return of a patient history and recommendations by CAIR to the EHR system. A formal testing and onboarding process for BiDX, independent of the current one-way data submission process is required. Onboarding of Sites to BiDX has begun. Sites interested in BiDX including data aggregators/HIEs) are required to complete the CAIR2 Bi-directional Data Exchange Interest/Readiness Survey. Interested sites should also review the CAIR2 Bi-directional (QBP/RSP) Data Exchange Implementation Guide for proper message formatting.  If you are a direct submitter (EHR to CAIR, no data aggregator/HIE), please consult with your EHR vendor support as to the bidirectional readiness of your EHR. Onbaording steps are described on the CAIR2 BiDX page.
  • To get the most value from the BiDX process, each site should consider submitting all active patient historical doses to CAIR so that patient vaccination recommendations returned to your EHR will be correct.  Consult with one of our CAIR Data Exchange Specialist about submitting prior immunizations records (historical data) for your active patients. 

Back to top

Will there be additional costs for bidirectional data exchange?

  • While access to CAIR is free, you will need to consult with your EHR vendor to determine if you current system is capable of bi-directional messaging and if there would be additional costs for implementation.

Back to top


Back to CAIR2 Overview